Roaccutane may lead to depression

Roaccutane, a member of the retinoid family, has been around since the 1980's. It is a member of the class of Vitamin A related compounds used to treat severe .

Since the drug was first introduced, there have been controversial complaints of depression and suicidal behavior in some group of people using Roaccutane.

Roche, the drug's manufacturer, has since included a warning label in the product information that mentions use of may cause depression, psychosis (loss of touch with reality) and suicidal behavior.

A new study examined the effects of on a group of mice, and found that mice who were administered Roaccutane spent more time immobilized and unresponsive to stress, compared to non-treated controls.

While the results of this study can not be applied directly to humans, it does show that the retinoid family of compounds may have wider nervous system effects than previously believed. Roaccutane is not prescribed to pregnant women for this reason.

Studies on people have been influenced by the fact that severe acne may lead to severe depression on its own; regardless of treatment. However, if you are currently taking Roaccutane and are finding yourself feeling blue, weepy, or listless, talk to your doctor about other treatment alternatives for your severe acne.

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